Vytorin study results

Vytorin Study: Disappointing Results - WebMD

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7/21/2008 · July 21, 2008 -- Researchers today reported disappointing results from a new study of Vytorin, which combines the unique cholesterol drug Zetia with …

Vytorin Study: Disappointing Results - WebMD

Vytorin Study Results Cause Stocks To Sink - CBS News

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1/16/2008 · Vytorin Study Results Cause Stocks To Sink ... Stanley analyst Jami Rubin wrote in a research report that the market appeared to be "overly pessimistic" about …

Vytorin Study Results Cause Stocks To Sink - CBS News

New England Journal of Medicine Publishes Vytorin IMPROVE ...

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6/17/2015 · June 17, 2015 - Merck announced that the New England Journal of Medicine published the results of the IMPROVE-IT trial, an investigational study comparing treatment with Vytorin (ezetimibe and simvastatin) to treatment with simvastatin alone. The trial assessed more than 18,000 patients presenting with acute coronary syndromes. The results of IMPROVE-IT were first presented at the American ...

New England Journal of Medicine Publishes Vytorin IMPROVE ...

Vytorin Study: Disappointing Results - CBS News

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study of Vytorin , which combines the unique cholesterol drug Zetia with simvastatin, a traditional statin drug sold generically and as Zocor . The study included some 1,800 adults with aortic ...

Vytorin Study: Disappointing Results - CBS News

Study Casts Doubts on Vytorin, Zetia - WebMD

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1/15/2008 · Jan. 15, 2008 -- Disappointing results from a long-awaited trial of the best-selling cholesterol drug Vytorin drew mixed reactions from some of the nation's leading cardiologists. In fact ...

Study Casts Doubts on Vytorin, Zetia - WebMD

Vytorin Study Results Disappoint - Diabetes Self-Management

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1/22/2008 · The newly released results of a preliminary study suggest that the drug Vytorin, which combines the cholesterol-lowering drug ezetimibe with a statin, may slow the growth of arterial plaque no more effectively than a statin taken alone. Because ezetimibe lowers cholesterol by …

Vytorin Study Results Disappoint - Diabetes Self-Management

Results from Investigational IMPROVE-IT Study of VYTORIN ...

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KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the New England Journal of Medicine published the results of the IMPROVE-IT trial, an investigational study comparing treatment with VYTORIN® (ezetimibe and simvastatin) to treatment with simvastatin alone in more than 18,0

Results from Investigational IMPROVE-IT Study of VYTORIN ...

Vytorin Reexamination Study (0653A-174) - Study Results ...

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Vytorin Reexamination Study (0653A-174) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.

Vytorin Reexamination Study (0653A-174) - Study Results ...

Ezetimibe Added to Statin Therapy after Acute Coronary ...

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Results. The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin–ezetimibe group, as compared with 69.5 mg per ...

Ezetimibe Added to Statin Therapy after Acute Coronary ...

Merck's Vytorin Study Epitomizes Inherent Risks Of Major ...

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12/16/2015 · Merck's Vytorin Study Epitomizes Inherent Risks Of Major Clinical Trials ... the IMPROVE-IT results would demonstrate that Vytorin reduced morbidity and mortality in patients with cardiovascular ...

Merck's Vytorin Study Epitomizes Inherent Risks Of Major ...

Ezetimibe/simvastatin - Wikipedia

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9/20/2005 · This is a randomized, active-control, double-blind study of subjects with stabilized high-risk acute coronary syndrome (ACS). The primary objective is to evaluate the clinical benefit of Ezetimibe/Simvastatin Combination 10/40 (single tablet, under the brand VYTORIN in the United States) compared with Simvastatin 40 mg.

Ezetimibe/simvastatin - Wikipedia

IMPROVE-IT: Examining Outcomes in Subjects With Acute ...

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3/31/2008 · Questions hover over Vytorin's worth - and late release of study The findings on the cholesterol drug showed no benefit to heart-disease patients.

IMPROVE-IT: Examining Outcomes in Subjects With Acute ...

Questions hover over Vytorin's worth - and late release of ...

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Vytorin (Ezetimibe & Simvastatin) is a prescription medicine used to decrease your blood's levels of "bad" cholesterol and triglycerides, while increasing your blood's level of "good" cholesterol.

Questions hover over Vytorin's worth - and late release of ...

Vytorin (Ezetimibe & Simvastatin) - Side Effects, Dosage ...

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In January 2008, Merck/Schering Plough Pharmaceuticals -- the maker of both Zetia and Vytorin -- released the results of a study on the effects of the combination of ezetimibe and high-dose simvastatin versus simvastatin alone on the atherosclerotic process in patients with heterozygous familial hypercholesterolemia, called the ENHANCE study.This study compared 720 patients taking either ...

Vytorin (Ezetimibe & Simvastatin) - Side Effects, Dosage ...

What You Need to Know About Zetia and Vytorin

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Ezetimibe is a drug that lowers cholesterol levels.It has been FDA approved since 2002, and is marketed as a stand-alone drug (Zeta) in combination with the simvastatin (a statin drug) as Vytorin. However, ezetimibe has been somewhat controversial since its introduction, and experts still argue about its appropriate place in the treatment of lipid disorders.

What You Need to Know About Zetia and Vytorin

The Debate Over Using Ezetimibe (Vytorin) for Cholesterol

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Merck, Schering-Plough agree to pay $5.4 million to resolve investigation by state attorneys generalSEATTLE – Marketers of the cholesterol-lowing drug Vytorin will pay $5.4 million to resolve an investigation by attorneys general into the companies’ delayed release of negative study results, Attorney General Rob McKenna announced today.

The Debate Over Using Ezetimibe (Vytorin) for Cholesterol

Delayed Vytorin study results a bitter pill for drug ...

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Those results suggested that while Vytorin cuts cholesterol, it does not reduce heart disease any more than a statin alone. Recently, researchers reported results from a study of Vytorin vs. Zocor alone in patients with narrowing of a major heart valve: the SEAS study, sponsored by …

Delayed Vytorin study results a bitter pill for drug ...

Is Vytorin Cancer Risk Real? - MedicineNet

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11/20/2010 · The long-awaited SHARP study has turned up positive results for Vytorin (ezetimibe and simvastatin) in a population of patients with chronic kidney disease. Results of SHARP (Study of Heart and Renal Protection) were presented on Saturday at the …

Is Vytorin Cancer Risk Real? - MedicineNet

SHARP Shows Benefit for Vytorin in Chronic Kidney Disease

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Already, the results of the Vytorin study have punished the two drugmakers, driving down shares of Merck 25 percent and Schering-Plough 30 percent so far this year.

SHARP Shows Benefit for Vytorin in Chronic Kidney Disease

In wake of Vytorin study, some heart doctors reassess LDL ...

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7/21/2008 · SEAS may have difficulty repairing that damage, because of the way the study is designed and also because it tests Vytorin in a very special group--those who have a condition called aortic ...

In wake of Vytorin study, some heart doctors reassess LDL ...

Key Vytorin Results Expected - forbes.com

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Results from Investigational IMPROVE-IT Study of VYTORIN® (ezetimibe and simvastatin) Published in the New England Journal of Medicine

Key Vytorin Results Expected - forbes.com

Results from Investigational IMPROVE-IT Study of VYTORIN ...

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11/10/2016 · Vytorin Side Effects Injury Lawsuits. On January 14, 2008, the results of a long-awaited study on the effectiveness of Vytorin to reduce artery clogging plaque …

Results from Investigational IMPROVE-IT Study of VYTORIN ...

Vytorin Lawsuits - Clogged Arteries Lawyers, Vytorin Lawsuits

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With updated results from a key medical study due out today, Merck and Schering-Plough unexpectedly delayed the release of their second-quarter financial results until after the closing bell. Matt ...

Vytorin Lawsuits - Clogged Arteries Lawyers, Vytorin Lawsuits

With Vytorin study results due today, Merck and Schering ...

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My understanding of the Vytorin study results is that while it reduces your cholesterol level, you may be able to do it less expensively by just bumping up the amount of the generic drug in the pill - BUT - they aren't quite sure yet. The people selected for the study fell into the group that had high cholesterol due to genetics. Like jim62 said, I wouldn't worry too much about the Vytorin ...

With Vytorin study results due today, Merck and Schering ...

vytorin test results - MedHelp

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The FDA's Endocrinologic and Metabolic Drugs Advisory Committee reviewed the SHARP study in November 2011 and voted unanimously in favor of approving Vytorin to reduce the risk of …

vytorin test results - MedHelp

Vytorin and Zetia Lower Cholesterol But Do They Improve ...

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WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved an updated label for VYTORIN® (ezetimibe/simvastatin) that includes results from the Study of Heart and Renal Protection (SHARP).

Vytorin and Zetia Lower Cholesterol But Do They Improve ...

Vytorin US Label Updated With SHARP Results - Medscape

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Under pressure from Congress and some doctors over the long-delayed study results Merck and Schering-Plough released the top-line results of the study in January, which showed Vytorin failed to ...

Vytorin US Label Updated With SHARP Results - Medscape

New FDA Approved Labeling For VYTORIN® (Ezetimibe ...

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3/29/2008 · U.S. researchers said on Friday they plan to expand the size of a major study to determine the heart benefits of the controversial cholesterol fighter Vytorin, which they said would delay results ...

New FDA Approved Labeling For VYTORIN® (Ezetimibe ...

Vytorin Study Shows Little Change In Artery Thickness

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2/1/2018 · Study of Heart and Renal Protection. In SHARP, 9270 patients were allocated to Vytorin 10/20 mg daily (n=4650) or placebo (n=4620) for a median follow-up period of 4.9 years. The proportion of patients who permanently discontinued study treatment as a result of either an adverse event or abnormal safety blood result was 10.4% vs. 9.8% among patients allocated to Vytorin and placebo, …

Vytorin Study Shows Little Change In Artery Thickness

Vytorin heart study expanded, results being delayed - Reuters

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Giugliano RP, Cannon CP, Blazing MA, et al., on behalf of the IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial) Investigators. Benefit of Adding Ezetimibe to Statin Therapy on Cardiovascular Outcomes and Safety in Patients With vs. Without Diabetes: Results from IMPROVE-IT. Circulation 2017;Dec 20:[Epub ahead of ...

Vytorin heart study expanded, results being delayed - Reuters

Vytorin - FDA prescribing information, side effects and uses

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1/15/2008 · As for the extended delay in reporting the results of the Vytorin study — called ENHANCE — Schering-Plough spokesperson Lee Davies told TIME that it was due to the time involved in reading and interpreting the tens of thousands of images of the carotid arteries that the study generated — data that had been available since April 2006.

Vytorin - FDA prescribing information, side effects and uses

IMProved Reduction of Outcomes: Vytorin Efficacy ...

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NEW YORK - Wall Street fluctuated today as investors worried about earnings at drug makers Merck & Co. and Schering-Plough Corp. Both pharmaceutical companies fell after a new study showed that ...

IMProved Reduction of Outcomes: Vytorin Efficacy ...

Is Vytorin a Failure? - TIME

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7/22/2008 · Vytorin: Another Round of Nasty Results By Derek Lowe 22 July, 2008 A report on another clinical study of Vytorin (ezetimibe), their drug with Schering-Plough, was coming out, so they put the numbers on hold until after the press release yesterday afternoon.

Is Vytorin a Failure? - TIME

Report: Vytorin results fall short of goal - philly.com

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Ezetimibe is a drug that selectively inhibits cholesterol absorption and further reduces LDL-C when used in addition to statins. The ENHANCE trial is a randomized study aimed at studying the ...

Report: Vytorin results fall short of goal - philly.com

Vytorin: Another Round of Nasty Results | In the Pipeline

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1/25/2012 · New FDA Approved Labeling For VYTORIN(R) (Ezetimibe/Simvastatin) Includes Results From the Study of Heart and Renal Protection (SHARP) in Patients With Moderate to Severe Chronic Kidney DiseaseFDA

Vytorin: Another Round of Nasty Results | In the Pipeline

The ENHANCE Trial: Analysis and Clinical Significance

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3/28/2008 · CHICAGO, March 28 (Reuters) - U.S. researchers said on Friday they plan to expand the size of a major study to determine the heart benefits of the …

The ENHANCE Trial: Analysis and Clinical Significance

New FDA Approved Labeling For VYTORIN(R) (Ezetimibe ...

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It is easy to understand why Merck and Schering-Plough would have wanted to hold back the results of the ENHANCE study. Vytorin sales make the companies billions each year, and the study’s findings put those sales at serious risk, as many doctors may opt to prescribe simvastatin (roughly $1 per pill) rather than Vytorin (about $3 per tablet).

New FDA Approved Labeling For VYTORIN(R) (Ezetimibe ...

UPDATE 2-Vytorin heart study expanded, results being ...

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U.S. researchers said on Friday they plan to expand the size of a major study to determine the heart benefits of the controversial cholesterol fighter Vytorin, which they said would delay results ...

UPDATE 2-Vytorin heart study expanded, results being ...

Vytorin® Lawsuit | Vytorin Side Effects Lawyer

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Merck's $688M Vytorin Settlement Wins Judge's Nod ... hard-fought litigation accusing the pharmaceutical giants of causing investor losses by concealing the results of a Vytorin clinical study ...

Vytorin® Lawsuit | Vytorin Side Effects Lawyer

Vytorin Heart Study Expanded; Results Delayed - CNBC

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1. After the publication of the ENHANCE trial results, there was a significant decrease in the number of new initiations of ezetimibe therapy. 2. There was also a significant increase in the number of discontinuations of ezetimibe therapy. Evidence Rating Level: 2 (Good) Study Rundown ...

Vytorin Heart Study Expanded; Results Delayed - CNBC

Merck's $688M Vytorin Settlement Wins Judge's Nod - Law360

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Results From the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) Study ... The study was initiated and designed by academic researchers in Scandinavia, and carried out at 173 clinical centres in Norway, Denmark, Sweden, Finland, Germany, UK and Ireland. ... Vytorin Efficacy International Trial) study is a randomized double-blind trial of ...

Merck's $688M Vytorin Settlement Wins Judge's Nod - Law360

Ezetimibe (Zetia, Vytorin) use declining after ENHANCE ...

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1/18/2008 · So many patients were stunned when Vytorin's makers, Merck & Co. and Schering-Plough Corp., on Monday finally released results of a study meant to …

Ezetimibe (Zetia, Vytorin) use declining after ENHANCE ...

Results From the SEAS (Simvastatin and Ezetimibe in Aortic ...

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The culmination of a six year study led by cardiologists at Duke University showcased the phenomenal benefits of cholesterol lowering agents Ezetimibe and Simvastatin, also known as the brand name drug Vytorin.Study results were conclusive in determining the importance of low LDL levels of cholesterol, with ultra-low levels being ideal.

Results From the SEAS (Simvastatin and Ezetimibe in Aortic ...

Vytorin study confuses patients, divides doctors - nbcnews.com

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The Senate Finance Committee said even the researcher who led a crucial study of the drug accused Vytorin makers Merck & Co. and partner Schering-Plough Corp. of withholding negative results to ...

Vytorin study confuses patients, divides doctors - nbcnews.com

Ezetimibe and Simvastatin Shine In Recent Study Results ...

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1/17/2008 · Results of the Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia (ENHANCE) study appear to indicate no benefit from the combination of ezetimibe (Zetia, Merck/Schering-Plough) and simvastatin (sold together as Vytorin, Merck/Schering-Plough) over …

Ezetimibe and Simvastatin Shine In Recent Study Results ...

Congress: Vytorin Makers Held Bad News - ABC News

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After results of the pivotal trials of ezetimibe easily met predefined safety and efficacy targets (with the latter based on the surrogate measure), further trials measuring longer-term, more ...

Congress: Vytorin Makers Held Bad News - ABC News

No difference between simvastatin and Vytorin ENHANCE ...

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1/18/2008 · So many patients were stunned when Vytorin's makers, Merck & Co. and Schering-Plough Corp., on Monday finally released results of a study meant to …

No difference between simvastatin and Vytorin ENHANCE ...

Premature Release of Data from Clinical Trials of ...

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A study released Jan. 14 by the makers of Vytorin found that the drug -- a combination of the Zocor (simvastatin) and Zetia (ezetimibe) -- may be no more effective at reducing the build-up of ...

Premature Release of Data from Clinical Trials of ...

Vytorin study confuses patients - Health - Heart health ...

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Vytorin study confuses patients - Health - Heart health ...

FDA Will Wait for Trial Results on Vytorin - ABC News

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FDA Will Wait for Trial Results on Vytorin - ABC News
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